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Lipid-OOH = lipid peroxide

With the caveat that certain aldehydes products (e.g

[DOI] [PubMed] [Google Scholar] Bradford BU, Kono H, Isayama F, et al

Characterization of a selenate-resistant Arabidopsis mutant

Although the actual mechanisms of MTX-induced liver and kidney damage are unknown, one of the hypotheses is the breakdown in cellular antioxidant defences, which increases the production of reactive oxygen species and nitrogen species, inhibits cytosolic NADP-dependent dehydrogenase and NADP malic enzyme, lowers glutathione (GSH), superoxide dismutase (SOD) and catalase levels and reduces the effectiveness of the antioxidant defence system protecting the cell against reactive oxygen species (Reference Savran, Cicek and Doguc7)

Amyloid 2025:111 van Jaarsveld PP, Edelhoch H, Goodman DS, Robbins J