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A 2019 meta-analysis in the journal Translational Psychiatry found that high-EPA omega-3 supplements significantly reduced depressive symptomsespecially when taken alongside antidepressants

doi: 10.1016/j.dnarep.2006.07.001 58 ColicchioR.RicciS.LambertiF.PagliaruloC.PagliucaC.BraioneV.et al

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Conclusion: Hence the subclinical hypothyroidism, prevalent in overweight individuals aged 46-60 particularly in female is very high compare to overt hypothyroidism, where TSH was positively correlated with the Glutathione peroxidase (GPx) and Malondialdehyde (MDA), representing increased TSH levels are associated with increased oxidative stress in body

Glutathione levels decline with age, so supplementing it could affect other processes of aging

doi: 10.1038/s41589-019-0462-8 51 JiangCShiQYangJRenHZhangLChenSet al