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Ciertas bacterias intestinales pueden convertir la L-carnitina en compuestos que luego forman TMAO en el hgado

No ocurri aumento de ALT o AST mayor a 3 veces el lmite superior normal en ningn paciente de los que recibieron monoterapia de estatinas en dosis bajas a moderadas

Researchers suggest that elevated gut pH, gut dysbiosis (i.e., a higher Firmicutes : Bacteroidetes ratio), obesity, or malabsorption might increase fecal SCFA, such as butyrate, which could have potential neurotoxic effects [25, 45, 46]

25 l was transferred into the Nucleofector cassette and electroporated using the CA-189 protocol (Zou et al, 2021)

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