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Despite the use of rodents and small mammals being commonplace in research, in particular for the development of novel therapeutic agents, caution still needs to be practiced when extrapolating research data to clinical applications

Tesofensine is a highly effective appetite suppressant that reduces cravings and overall food intake by acting on neurotransmitters that regulate hunger

WRN as a Novel Target of Synthetic Lethality: Current Advances and Future Perspectives. Journal of Medicinal Chemistry 68: 1321813245

Systemic manifestations may include arthritis, interstitial lung disease (ILD), renal and nervous system involvement, and an increased risk of lymphoma (202)