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3.1 Roles of ROS and NO in the pathophysiology of human diseases 3.1.1 Oxidative stress, ROS, inflammatory markers and different types of cancer: Connecting the dots 3.1.1.1 Role in carcinogenesis The mechanism of carcinogenesis is divided into different stages: progression, promotion, and initiation

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A major strength of this study is the extensive metabolic profiling of tissue-specific IR in both the fasting and the postprandial state, thereby broadening and deepening the characterization of plasma lipid profiles in tissue-specific IR and providing more insights into the metabolic abnormalities that are related to muscle or liver IR