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This promotes Nrf2 nuclear translocation and ARE binding, upregulating antioxidant enzymes such as Superoxide Dismutase 1(SOD1), Heme Oxygenase-1(HO-1), and Glutathione Peroxidase (GPx) (Wang et al., 2020

Combination of GSH, amikacin and DNase-I showed the greatest reduction in MRAB biofilm viability

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Similarly, in glioblastoma stem-like cells, autophagy inversely correlates with the response to temozolomide, and its inhibition improves treatment efficacy

While progestin-based therapies are effective in many women, a substantial percentage of endometriosis patients exhibit progesterone resistance and therefore have insufficient therapeutic responses to these treatments