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Data availability Source data are provided with this paper

In Europe, the prevalence is about 2.1%, with an annual incidence of 1.3 per 1,000 individuals

Walker et al., 1991), and the second was the advent of molecular techniques, which led to the cloning, and characterization of the human GHR , thus initiating the understanding of the pathophysiology of GHI (Amselem et al., In medicine, scientific advances often move more rapidly than the practices of clinicians, who may remain attached to the recognized, and trusted view of a certain disorder, particularly if it is rare

Thus, gMG can be caused by IgGs of different subclasses that bind different targets

5.7 Vitamin B7 In this subsection Vitamin B7 (Biotin) is presented.Although biotin can be found in many foods that are included in a typical diet, it usually appears in a form that is bonded to proteins and cannot be readily utilized by cells

After washing, bound proteins were eluted and analyzed by SDS-PAGE followed by CBB staining