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Considerable increases in the mean MSIS (Multiple Sclerosis Impact Scale) -29-PHYS (Physical) and MSIS-29-PSYCH (Psychological) item-scores in the mitoxantrone-treated group were noted in relation to the other groups

Mechanism clarity: Is there a plausible biological reason this compound would help (e.g., antioxidant activity, hormone modulation)

doi: 10.1590/0004-282X20160116 9

Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors