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10.1016/j.nbd.2008.04.007 311 ZhaoC.FancyS

Zhang X, Tao W, Mak PY, Qi Y, Ma W, Wang J, Ruvolo V, Andreeff M , Carter BZ

PMID 6137189

In these cases, injections or very high-dose oral therapy that bypass absorption limits may be necessary to correct deficiency and, in turn, restore appetite

These assessments included: (1) ease of use of the treatment, rated on a five-point Likert scale (0 = very easy, 1 = easy, 2 = neutral, 3 = difficult, 4 = very difficult)

But in both tau pathologies, tau buildup and the neurofibrillary tangles formed from tau eventually disrupt brain cells ability to communicate with other cells