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Results Two successive glutathione synthetase gene family expansions have occurred during the evolution of cyst and reniform nematode obligate biotrophic interactions We analysed the genomes and/or transcriptomes of eleven plant-parasitic and non-plant-parasitic nematode species ( Caenorhabditis elegans , Bursaphelenchus xylophilus , Longidorus elongatus , Pratylenchus penetrans , Meloidogyne incognita , Nacobbus aberrans , Rotylenchulus reniformis , Globodera rostochiensis , G

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In addition, this deletion completely cancels the increase in ROS production caused by the gmhA deletion , while all other mutations in the genes that regulate the metabolism of cysteine and glutathione, as well as a violation of cystine transport, lead to an even greater increase in the level of ROS in cells with a gmhA deletion