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818 Ferroptosis in renal ischemia-reperfusion injury The kidney is extremely sensitive to I/R injury, and the mismatch between oxygen supply and oxygen demand leads to decreased oxidative metabolism, resulting in progressive damage of renal tubular epithelial cells

10.1021/acschemneuro.8b00683 ACS Chem

It is found in nearly every cell in the human body, but it is most concentrated in the liver, where it assists in filtering toxins

Accumulation of MYOC in the trabecular meshwork caused by mutations leading to overproduction or reduced degradation is associated with increased IOP and, ultimately, with the development of glaucoma (Doucette et al., 2015)

Oxyresveratrol alleviates hepatic steatosis by activating AMPK and inhibiting SREBP-1cmediated lipogenesis, demonstrating anti-NAFLD efficacy comparable to atorvastatin in animal models (51)