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Description

They reported that p53 suppresses accumulation of cytoplasmic chromatin fragments (CCF), including DNA damage signaling marker H2A.X, and its downstream inflammatory phenotype (e.g., SASP) of monocytes and macrophages in liver

10.1021/acssynbio.2c00392

All procedures were approved and conducted per the University Committee on Animal Resources at the University of Rochester Medical Center (UCAR #2010-024E, UCAR-2008-016E)