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Cellular and molecular mechanisms of glioblastoma malignancy: implications in resistance and therapeutic strategies

Immunotherapies, small molecules targeting -Syn oligomers, and gene-silencing technologies show potential in mitigating neurotoxicity and slowing disease progression [178-180]

AXM consists of 3% (w/v) yeast extract (for growth factors and vitamins) (BectonDickinson, Franklin Lake, NJ) and 3% (w/v) soy peptone (for a supply of amino acids) (Sigma-Aldrich, St

High homocysteine levels are problematic because they have been linked to heart disease and atherosclerosis.32 In people who are deficient or have mutations in the enzymes that catalyze the production of glutathione from homocysteine, the methylation cycle will be under pressure to remove excess homocysteine

Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14S) and its mixed disulfide with glutathione