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In fact, melatonin ameliorated the antioxidant defenses of the animals by improving the Nrf2 and BNDF expression

Apr 2018;66(2):152-159

The approval is backed by data from the pivotal Phase III PERSEUS study, where treatment with subcutaneous Darzalex Faspro reduced the risk of disease progression or death by 60% in the intended patient population compared to standard of care