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Description

5.1.2 Thioredoxin reductase Thioredoxin reductase (TrxR) is a homodimeric enzyme that boasts a sophisticated architecture, featuring a flavin adenine dinucleotide (FAD) and a reduced nicotinamide adenine dinucleotide phosphate (NADPH) binding site for each of its monomers, thereby facilitating its essential role in cellular redox homeostasis (183)

Concentrations of GSH, GSSG and the ratio between GSH and GSSG (GSH/GSSG), used as a proper value to evaluate the redox balance in these cells, are reported in Table 2