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The 21 days period of treatment with curcumin and piperine resulted in a more significant improvement compared to isolated treatment with curcumin

Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication

In addition, any factors that impair blood flow to the local tissue will affect the rate and extent of drug absorption

[3H]bumetanide binding and inhibition of Na+ + K+ + Cl-co-transport: demonstration of specificity by the use of MDCK cells deficient in co-transport activity