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Outcome measures The primary outcome was the effect of KD on clinical phenotypes (epilepsy, muscle involvement, tonus dysregulation (muscular hyper- or hypotonia), movement disorders, developmental delay and intellectual disability (DD/ID), other individual signs and symptoms) and the occurrence of adverse events (AEs)

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J Pharmacol Exp Ther 324:814 Baud FJ, Bismuth C, Garnier R, Galliot M, Astier A, Maistre G, Soffer M (19861987) 4-Methylpyrazole may be an alternative to ethanol therapy for ethylene glycol intoxication in man

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The endocrine implications of this phenomenon, however, were not sufficiently emphasized in the discussion