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Functionalization of PLGA nanoparticles could further enhance BBB targeting making them advantageous for delivering therapeutic agents to manage PD and other CNS disorders 99

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FiO 2 , fraction of inspired oxygen

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They are commonly used in drug delivery systems as they provide numerous benefits including improving drug properties such as biocompatibility and solubility, which typically hinder the effectiveness of a drug (Yang and Gao, 2017)