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In our study, the ACTH levels might have possibly increased more gradually after the activation of the HPA-axis in response to the psychological stressor, and this might have resulted in a delayed feedback and therefore a longer cortisol response compared to physiological validation studies

This is a clinically important interaction that requires awareness, particularly in perioperative settings

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Although we typically associate NAC with acetaminophen toxicity, a prospective trial showed that NAC improved transplant-free survival in other etiologies of acute liver failure, most significantly in cases of DILI or HBV with coma grades I-II

In this series, we will examine treatment concepts to minimize these issues in cooling networks, including once-through systems, open-recirculating systems with cooling towers, and closed systems

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