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Furthermore, EF24 induces ferroptosis in osteosarcoma cells by increasing the levels of lipid peroxides and intracellular iron ions

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In contrast, melatonin inhibits severe inflammation

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In addition, HSV-1 has been reported to induce apoptosis in brainstems of mice infected with this virus, in which significant TUNEL-staining was observed at day 6 post-infection, although with low levels of detectable infectious virus, suggesting death of cells that were bystander to those infected with HSV-1 (Shaw et al., 2002)