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HGH deficiency has been associated with memory problems, fatigue, sleep disturbances, and attention deficits, which negatively affect individuals emotional wellbeing and quality of life (Nyberg and Mathias Hallberg, 2013

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Interleukin-6 (IL-6), tumor necrosis factor- (TNF-), nuclear factor erythroid 2-related factor 2 (NRF2), nuclear factor-B/P65 (NF-B/P65), superoxide dismutase type 1 (SOD1), caspase-1 (Casp-1), AQP1, AQP2, and kidney injury molecule-1 (KIM-1) were the primers used in the PCR that was conducted using a thermal cycler (A200 Gradient Thermal Cycler, LongGene , Hangzhou, China) (Supplementary Table S1)