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Esteghamati et al

A washout period of at least several weeks is advisable, though specific recommendations cannot be made given limited data

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Symptom Monitoring: Even though serious adverse events did not occur in trials, individual monitoring for headache, gastrointestinal symptoms, or unusual effects allows for early detection of tolerability issues and appropriate management adjustments

Significant allergic reactions, though rare, require stopping use and potentially seeking medical attention

5-Amino-1MQ has shown to inhibit NNMT, preventing Nicotinamide from entering the NAD+ Salvage Pathway and converting into NAD+