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Thornsberry C, Brown NP, Draghi DC, Evangelista AT, Yee YC, Sahm DF

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But theres another catch, because cysteine cannot be given as such, we had to supplement it in another form called N-acetylcysteine. In past studies, Sekhar and his colleagues determined that supplementing GlyNAC, a combination of glycine and N-acetylcysteine, corrected glutathione deficiency inside the cells of naturally aged mice to the levels found in younger mice

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To determine if CHCHD2 KO impacted mitochondrial respiration in GBM cells, a mitochondrial stress test was conducted on U87vIII CHCHD2 WT and KO cells using a Seahorse XFp Extracellular Flux Analyzer ( Figure 3B ) [35]