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Elevated levels of 8-oxoGsn in urine and cardiac tissues have been observed in HF, correlating positively with heart failure indicators

138 WangY.ShiJ.DaiD.CaiJ.WangS.HongY.et al (2022)

C11-BODIPY 581/591 was prepared as a 5 M working solution in HBSS and added to cells along with 1 g/ml Hoechst 33258 stain (Cat

Highly reactive oxygen-containing molecules such as superoxide (O), hydrogen peroxide (HO), hydroxyl radicals (OH) and peroxyl radicals (OOH) that are by-products of cellular metabolism that at low levels function in cell signalling and immune defence, but when produced in excess result in oxidative stress, damaging cellular structures such as DNA, proteins and lipids