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This metabolic reprogramming maintains the level of NADPH to counter hypoxia- or chemotherapy-induced ROS stress and plays a role in BCSC enrichment and lung metastasis 53,54

Sadly, this antioxidant molecule is one of the most misrepresented Golden Age agents in the entire optimization space

L-NAME + L-arginine + BPC 157)

In fact, MOTS-c levels naturally rise during exercise, and giving MOTS-c to mice has been shown to enhance their physical performance (they can run longer on a treadmill)