2.7 Cutting-edge directions and future prospects of neuronal metabolism research Looking ahead, integrating multi-omics approaches such as 4-dimensional fast data-independent acquisition (4D-FastDIA) quantitative proteomics and targeted metabolomics [e.g., dissecting how Danggui-Shaoyao-San regulates the glycogen synthase kinase 3 beta (GSK3)/PGC1 signaling pathway to improve brain glucose uptake and mitochondrial complex function in AD models (Wu et al., 2024)] with computational modeling is unraveling systematic regulatory networks in neuronal energy metabolism, pinpointing critical nodes like pyruvate dehydrogenase complex phosphorylation and dynamic MCT2 transporter expression (Brown and Ransom, 2007)
doi: 10.1016/j.stem.2016.12.001 92 ZhangGJiangCWangZChenWGuWDingY
Patients with a history of severe TBI may not make the quick recovery that many of our post-concussion patients experience, but they often make significant progress at our clinic
This review provides a comprehensive overview of the current understanding of copper's regulatory mechanisms in health and disease, with particular emphasis on its roles in neurodegenerative disorders and cancer
10.1123/ijsnem.23.5.522 32 HoutvastD
At the 2017 Lucerne Festival, he performed the Swiss premiere of Michael Van der Aas multimedia cello concerto Up-close, as well as the world premiere of Luca Francesconis Das Ding Singt (commissioned for him by the Lucerne Festival), conducted by Matthias Pintscher