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Considering all these aspects, antioxidants appear to be a pathogenesis-oriented approach to combat the progression and symptoms of DPN [172,173]

Acetate reprograms gut microbiota during alcohol consumption

Subsequent introduction of two random mutations, Y444A and G484A, to D433N EcGGT variant further enhanced catalytic efficiency for GL-7-ACA substrate by 50-fold (Yamada et al., 2008)