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If gut health is the priority, a fiber-rich diet and good sleep do as much heavy lifting as any supplement

Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage

Engert V, Pruessner JC

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The average onset is between 18 and 29 years of age, with relatively few cases occurring before puberty or after menopause, suggesting a possible influence of androgenic hormones on skin keratinization