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Moreover, the inactivation of ubiquitination and proteasomal degradation of -catenin in the intact destruction complex have been shown to saturate the destruction complex, preventing further engagement and thereby degradation of -catenin (Li et al., 2012)

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Approximately 90% of ALS cases are sporadic ALS, with less than 10% being inherited (familial ALS)

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Lee YJ, Han S, Nam SY, Oh KW, and Hong J

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