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PMC4508379 Pickart, L., et al

Digestive discomfort, whether constipation or diarrhea, can disrupt your everyday life, while chronic digestive problems can have an even bigger impact on your long-term quality of life, from pain and embarrassment to missed time with loved ones and increased cancer risk

[DOI] [PubMed] [Google Scholar] 117.Murphy R, Stewart AW, Braithwaite I, Beasley R, Hancox RJ, Mitchell EA

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1 Introduction Melatonin, a hormone produced by the pineal gland, has garnered significant attention owing to its role in reproductive system regulation ( The suprachiasmatic nucleus in the anterior hypothalamus governs the biological clock, maintains circadian rhythms, and synchronizes physiological processes with the natural lightdark cycle ( Melatonin regulates circadian rhythms and significantly influences various aspects of fertility, including the timing of ovulation, sperm production, and embryo implantation ( The potential role of melatonin in ART has recently garnered significant interest