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B12 injections are medically indicated for individuals with a diagnosed B12 deficiency or conditions that impair B12 absorption, such as pernicious anemia, Crohns disease, celiac disease, or a history of gastric bypass surgery

ISoOR Perspective If we had to identify a single factor that may be limiting broader clinical adoption, our answer would be: Lack of standardization

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Regardless, the clinical safety in humans is still largely unknown

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Anyone selling you a precise human bioavailability figure is guessing