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1 (download XLSX Source Data of Fig

Notably, by using a Met antagonist (ethionine) and a product of Met metabolism (SAM) in vitro , Ikeda et al

Further highlighting the functional relationship between Ec CnoX and GroEL/ES, GroEL/ES obligate substrates are over-represented in the proteins found in a mixed-disulfide complex with Ec CnoX ( Our Working Model By joining the pieces of the Ec CnoX puzzle, we came to the following model (Figure 2)