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114,115,116 The conflicting conclusions may be attributed to the diverse sample sizes utilized across the studies, thus warranting more comprehensive investigations in large population cohorts using advanced genome-wide techniques

Chronic B12 deficiency patients require indefinite therapy with regular monitoring

Yes, B12 is non-toxic in high doses and considered safe [*]

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Progress is tracked with meaningful outcomes, such as improved standing tolerance, longer walking distance, fewer night flares, and better balance on stairs

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