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The model was further validated by assessing the interaction interface using known binding residues from previous experimental studies as references

doi: 10.1111/all.15666 33 RanjbarMWhetstoneCEOmerHPowerLCusackRPGauvreauGM

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Meanwhile, AMPK, as an energy sensor, its activation not only suppresses inflammatory signaling but also induces autophagy and antioxidant responses, working synergistically to improve barrier function [453, 454]

Glutathione can also rapidly break down into amino acid components in plasma, limiting its sustained effectiveness unless administered repeatedly

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