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Long-Acting Amylin Agonist AZD6234 AZD6234 is a novel long-acting selective AMY3R agonist developed by AstraZeneca for SC administration, and is currently in phase 2 testing [114]

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On the contrary, IGF-I bioactivity is increased in the maternal circulation resulting from increased total serum IGF-I and decreased binding affinity of fragmented IGFBP-3 (122)

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