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Rights and permissions About this article Cite this article Tu, Z., Zhong, Y., Hu, H

Next, glutaminases (GLSs), including glutaminase 1 (GLS1), glutaminase 2 (GLS2) and GAC (a splicing isoform of GLS1), convert Gln to glutamate (Glu) in the mitochondria, releasing ammonium ions ( Figure 1 ) (14)