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For instance, lower levels may play a role in many conditions that are more likely to develop in elderly people

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Fourth, clinical translational potential is underdeveloped: there is a lack of clinical cohort data to confirm whether ferroptosis biomarkers (e.g., GPX4 downregulation and lipid peroxide accumulation) are elevated in kidney stone patients, and preclinical studies have not addressed whether targeting ferroptosis can reduce stone formation or recurrence (rather than just protecting tubular cells in vitro )

KEGG pathway enrichment analysis indicated that important signaling pathways, including those involved in cell proliferation, axon guidance, neuroactive ligand-receptor interactions, and neurotrophic factors, were modulated by EW