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1 Background Cannabis has been used for its medicinal effects for almost five thousand years - the first mention comes from China and dates back to 2737 BC (Zuardi, 2006)

This rare side-effect was observed in 15 cases out of 8.9 million J&J doses administered in the US

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doi: 10.1016/S0140-6736(97)06467-2 53 ClemmonsDRMosesACSommerAJacobsonWRogolADSleeviMRet al

The peroxisomal membrane also harbors a small NAD(P)H-dependent ETC composed of NADH and cytochrome b, which uses molecular O 2 as the terminal electron acceptor, releasing O 2 into the cytosol