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CXCL2 activates the NOTCH/recombining binding protein suppressor of hairless (RBPJ) signaling pathway, leading to upregulation of CD44 on monocytes

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It influences anti-inflammatory pathways, including downregulation of cytokines (Tumor Necrosis Factor-alpha and Interleukin-6), which are responsible for promoting tissue swelling and damage

This is good news for a sunscreen agent as it needs to be on the surface of the skin to do its job properly

That is why they are commonly paired together in the Wolverine Stack