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Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR et al (2017) American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart Disease and Stroke Statistics-2017 update: a report from the American

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doi: 10.3390/nu14091987 3 IcardPShulmanSFarhatDSteyaertJMAlifanoMLincetH

Brain Behav Immun 38:112 Round JL, Mazmanian SK (2009) The gut microbiota shapes intestinal immune responses during health and disease

This implies AtGLYI to be the most important gene for MG detoxification

The increased activity of -secretases and concurrent reduction in the activity of -secretase may partially explain why melatonin treatment results in diminished A levels in the brains of both sporadic and transgenic animal models of AD [55,56,57]