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Combining them may help stabilize mood and reduce symptoms of anxiety or depression related to stress

Increased ECM stiffness engages innate immunity (e.g., tenascin C-CD47 phagocytic signaling in macrophages), underscoring immune regulation in the TME [42]

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Increased membrane lipid peroxidation depends on polyunsaturated fatty acid-containing phospholipid (PUFA-PL) synthesis, iron metabolism, and mitochondrial metabolism 12