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A p -value of less than 0.05 was considered to indicate significance

O'Hare et al., 2024

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[email protected] He, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

First, the chemical identification was performed once, with the methodology of the 1970s, and was not subsequently re-verified by modern peptide sequencing a point Kovalzon and Strekalova later flagged as a source of doubt about whether the isolated nonapeptide was a single defined entity or a mischaracterized fraction of a larger precursor (Kovalzon & Strekalova, 2006)

In the 2-year study, kava doses were 0, 0.1, 0.3, or 1.0 g/kg of bodyweight