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Ustekinumab (Stelara) is an IL-12 and IL-23 blocker that has FDA approval to treat various types of psoriasis

81 However, the potential consequences of chronic MPO inhibition in individuals with COPD who are already at an increased risk of pulmonary inflammation and infection are unknown

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doi: 10.1038/srep37789 105 HussaartsLGarca-TardnNvan BeekLHeemskerkMMHaeberleinSvan der ZonGCet al

Lipids actively participate in or mediate multifaceted effects on skin and immune cells residence and infiltration in inflammatory settings