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Both iron overload and deficiency can cause various disorders and human diseases

NLRP3 inflammasome regulates various inflammatory and autoimmune disorders (Li et al., 2020), demethyleneberberine (Zhao et al., 2022b), evodiamine (Shen et al., 2019), heterophyllin B (Gao et al., 2019), nigakinone (Liu et al., 2023), 8-Oxypalmatine (Mai et al., 2019), sinomenine hydrochloride (Zhou et al., 2021), and sanguinarine (Li et al., 2022b)], 7 phenylpropanoids [bergenin (Lopes de Oliveira et al., 2019), cinnamaldehyde (Tan et al., 2023), chlorogenic acid (Zeng et al., 2020), ferulic acid (Yu S

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Broad-spectrum or specific inhibition of caspase activityfor example, the use of 50 M Z-VAD-FMK in a Brucella abortus infection modelcan significantly reduce the Annexin V-positive rate of osteoprogenitor cells, suppress apoptosis in osteoblasts and macrophages induced by infection, and alleviate bone and joint destruction (Scian et al., 2012)

parapsilosis ( Zhai et al., 2024)