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Description

Neuronal induction of BNIP3-mediated mitophagy slows systemic aging in Drosophila

Downstream, master transcriptional regulators including c-Myc, HIF-1, and estrogen-related receptor are activated, collectively inducing the expression of rate-limiting glycolytic enzymes such as HK2 and PKM2 (74, 79)

Croese et al ., Reference Croese, O'neil, Masson, Cooke, Melrose, Pritchard and Speare2006

The nanoparticles were prepared using an emulsion solvent evaporation method, yielding particles with a mean size of 148.2 4.2 nm, a PDI of 0.12, and a zeta potential of 23.1 3.0 mV, supporting their suitability for BBB penetration