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In the event of cerebral hemorrhage, blood vessels rupture, leading to the release of a substantial amount of blood and hemoglobin (43)

doi: 10.1016/j.jaut.2022.102976 102 BalmerMMaEBantugGGrhlertJPfisterSGlatterTet al

Targeting autocrine CCL5-CCR5 axis reprograms immunosuppressive myeloid cells and reinvigorates antitumor immunity

E.WangX.LiS.LiX

PMID: 236 TsvitmanICastelOCDaganE

CB-1158 could block myeloid cell-mediated inhibition of T cell proliferation, increase the number of tumor-infiltrating CD8 + T cells and NK cells, and increase the expression of inflammatory factors and interferon-, thereby changing the immune microenvironment to promote inflammation and reduce tumor immune escape, inhibiting tumor cell proliferation