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Some studies had already confirmed that PQQ prevents oxidative damage in the brain and reduces the cognitive deficit caused by oxidative stress in rats during aging 52

In patients with AA, lipid peroxidation was found to be significantly higher than controls, indicating lower antioxidant activity in the hair follicles of those affected

Still, these molecules also have multiple GSH-independent functions, which can potentially confound interpretations

Real-world data offers a unique opportunity to better understand the disease as it exists in routine clinical practice

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As explained above, the present invention relates to the treatment or prevention of diabetes, obesity, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH), a cardiovascular disease or any other disease/disorder involving GLP-1 (including any disease/disorder involving, or mediated by, a deficiency of GLP-1 or deficient GLP-1 signalling), using the solid oral pharmaceutical composition provided herein