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Conversely, for Group 3 DEGs ( Tbx1 +/ -unique genes), we identified pathways involved in the fatty acid metabolism (mainly down-regulated genes) and axon guidance process (up-regulated genes) (Fig 5B)

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Originally characterized at the University of Florida by the Stephen ORahilly and Robert Kraft groups, the compound has been studied in preclinical research for body composition, adipose tissue lipolysis, glucose homeostasis, skeletal muscle aging, and metabolic disease endpoints

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