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In the pooled neuropathic pain trials submitted to the FDA, dizziness occurred in 29% and somnolence in 22% of pregabalin-treated patients versus 8% and 7% of placebo, respectively [4]

10.3389/fmicb.2020.00439 171 NunesA

Uncoupling proteins (UCP) Located in the mitochondrial inner membrane, uncoupling proteins (UCP) are a heterogeneous family of proteins that play an important role in partially dissipating the proton electrochemical gradient across the membrane (220)

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Activity of enzyme was determined in 100 mM potassium phosphate buffer (pH 6.5) with 1 mM l-chloro-2,4-dinitrobenzene (CDNB) and 4 mM GSH as substrates by following the change in absorbance at 340 nm ( 9.6 mM 1