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doi: 10.3389/fphys.2023.1303815 Received 28 September 2023 Accepted 22 November 2023 Published 04 December 2023 Volume 14 - 2023 Edited by Andrea Gerbino, University of Bari Aldo Moro, Italy Reviewed by Ioannis Tsamedidis, Aristotle University of Thessaloniki, Greece Maria Giulia Lionetto, University of Salento, Italy Updates Copyright 2023 Remigante, Spinelli, Patan, Barreca, Straface, Gambardella, Bozzuto, Caruso, Falliti, Dossena, Marino and Morabito

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These findings prompted further investigation into the synthetic version of the peptide, now known as Epithalon, to better understand its mechanisms of action and potential applications in human health

Ac-SDKP ameliorates the progression of experimental autoimmune encephalomyelitis via inhibition of ER stress and oxidative stress in the hippocampus of C57BL/6 mice